The burrito method is what works best for me. I always ask for
medications in liquid form, get a large towel and in one quick swoop,
roll up a cat. Only the ****ed face sticks out, and I stick the
squirter thing in the corner of the mouth. Head tipped back, and he
has no choice but to swallow.

Followed by a treat and lots of "Good boy."

After a couple of weeks on antibiotics recently, my big cat saw the
green towel and tried to run. Poor guy ran and got ON the bed. I guess
he thought that was a safe spot, but turns out it wasn't.