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another FeLV testing question
I recently rescued a kitten estimated at 6 months old. She has been spayed,
vaccinated, and tested negative for FIV/FeLV (snap test). My concern is that if she has been recently exposed, it could be too early for an accurate test. She has been isolated from my other kitties in a spare bedroom for 16 days since she was tested. Is 16 days too early for a re-test? What is the incubation period for FeLV? Thanks, Ben |
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"Ben Katz" wrote in message ... I recently rescued a kitten estimated at 6 months old. She has been spayed, vaccinated, and tested negative for FIV/FeLV (snap test). My concern is that if she has been recently exposed, it could be too early for an accurate test. She has been isolated from my other kitties in a spare bedroom for 16 days since she was tested. Is 16 days too early for a re-test? What is the incubation period for FeLV? FeLV infections don't work that way since the virus is transmitted "ready to use". The ELISA Snap test is about 100 times more sensitive than the IFA and can detect P27 antigen in circulating cells in the blood within a few days after transmission. The ELISA detects early infections, transient infections, and sequestered infections whereas the IFA usually does not because IFAs depend upon advanced stages of infection. Neither the ELISA or IFA will detect a latent infection because P27 is not produced during latency. However, latency may be an extension of the post-viremia recovery process and not a stage of the initial infection process itself. Other than transmission from a bite wound, effective transmission requires prolonged intimate contact. If I were you, I'd retest the cat with another ELISA. False ELISA-negatives are rare. In the unlikey event the ELISA is positve, retest with the IFA. FeLV ELISA positives are not all that reliable because a positive result indicates cirulating antigen but *not* necessairly a productive, marrow-origin infection. Good luck. Phil. |
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"Ben Katz" wrote in message ... I recently rescued a kitten estimated at 6 months old. She has been spayed, vaccinated, and tested negative for FIV/FeLV (snap test). My concern is that if she has been recently exposed, it could be too early for an accurate test. She has been isolated from my other kitties in a spare bedroom for 16 days since she was tested. Is 16 days too early for a re-test? What is the incubation period for FeLV? FeLV infections don't work that way since the virus is transmitted "ready to use". The ELISA Snap test is about 100 times more sensitive than the IFA and can detect P27 antigen in circulating cells in the blood within a few days after transmission. The ELISA detects early infections, transient infections, and sequestered infections whereas the IFA usually does not because IFAs depend upon advanced stages of infection. Neither the ELISA or IFA will detect a latent infection because P27 is not produced during latency. However, latency may be an extension of the post-viremia recovery process and not a stage of the initial infection process itself. Other than transmission from a bite wound, effective transmission requires prolonged intimate contact. If I were you, I'd retest the cat with another ELISA. False ELISA-negatives are rare. In the unlikey event the ELISA is positve, retest with the IFA. FeLV ELISA positives are not all that reliable because a positive result indicates cirulating antigen but *not* necessairly a productive, marrow-origin infection. Good luck. Phil. |
#6
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Are your other cats FELV?
-- Panther TEK: Staying On Top Of All Your Computer Needs! www.members.cox.net/catprotector/panthertek Cat Galaxy: All Cats, All The Time! www.catgalaxymedia.com "Ben Katz" wrote in message ... I recently rescued a kitten estimated at 6 months old. She has been spayed, vaccinated, and tested negative for FIV/FeLV (snap test). My concern is that if she has been recently exposed, it could be too early for an accurate test. She has been isolated from my other kitties in a spare bedroom for 16 days since she was tested. Is 16 days too early for a re-test? What is the incubation period for FeLV? Thanks, Ben |
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Are your other cats FELV?
-- Panther TEK: Staying On Top Of All Your Computer Needs! www.members.cox.net/catprotector/panthertek Cat Galaxy: All Cats, All The Time! www.catgalaxymedia.com "Ben Katz" wrote in message ... I recently rescued a kitten estimated at 6 months old. She has been spayed, vaccinated, and tested negative for FIV/FeLV (snap test). My concern is that if she has been recently exposed, it could be too early for an accurate test. She has been isolated from my other kitties in a spare bedroom for 16 days since she was tested. Is 16 days too early for a re-test? What is the incubation period for FeLV? Thanks, Ben |
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