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another FeLV testing question



 
 
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  #1  
Old December 11th 03, 04:29 PM
Ben Katz
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Default another FeLV testing question

I recently rescued a kitten estimated at 6 months old. She has been spayed,
vaccinated, and tested negative for FIV/FeLV (snap test). My concern is that
if she has been recently exposed, it could be too early for an accurate
test. She has been isolated from my other kitties in a spare bedroom for 16
days since she was tested. Is 16 days too early for a re-test? What is the
incubation period for FeLV?

Thanks,

Ben


  #4  
Old December 11th 03, 10:50 PM
Phil P.
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Posts: n/a
Default


"Ben Katz" wrote in message
...
I recently rescued a kitten estimated at 6 months old. She has been

spayed,
vaccinated, and tested negative for FIV/FeLV (snap test). My concern is

that
if she has been recently exposed, it could be too early for an accurate
test. She has been isolated from my other kitties in a spare bedroom for

16
days since she was tested. Is 16 days too early for a re-test? What is

the
incubation period for FeLV?


FeLV infections don't work that way since the virus is transmitted "ready to
use". The ELISA Snap test is about 100 times more sensitive than the IFA
and can detect P27 antigen in circulating cells in the blood within a few
days after transmission.

The ELISA detects early infections, transient infections, and sequestered
infections whereas the IFA usually does not because IFAs depend upon
advanced stages of infection. Neither the ELISA or IFA will detect a
latent infection because P27 is not produced during latency. However,
latency may be an extension of the post-viremia recovery process and not a
stage of the initial infection process itself.

Other than transmission from a bite wound, effective transmission requires
prolonged intimate contact. If I were you, I'd retest the cat with another
ELISA. False ELISA-negatives are rare. In the unlikey event the ELISA is
positve, retest with the IFA.

FeLV ELISA positives are not all that reliable because a positive result
indicates cirulating antigen but *not* necessairly a productive,
marrow-origin infection.

Good luck.

Phil.



  #5  
Old December 11th 03, 10:50 PM
Phil P.
external usenet poster
 
Posts: n/a
Default


"Ben Katz" wrote in message
...
I recently rescued a kitten estimated at 6 months old. She has been

spayed,
vaccinated, and tested negative for FIV/FeLV (snap test). My concern is

that
if she has been recently exposed, it could be too early for an accurate
test. She has been isolated from my other kitties in a spare bedroom for

16
days since she was tested. Is 16 days too early for a re-test? What is

the
incubation period for FeLV?


FeLV infections don't work that way since the virus is transmitted "ready to
use". The ELISA Snap test is about 100 times more sensitive than the IFA
and can detect P27 antigen in circulating cells in the blood within a few
days after transmission.

The ELISA detects early infections, transient infections, and sequestered
infections whereas the IFA usually does not because IFAs depend upon
advanced stages of infection. Neither the ELISA or IFA will detect a
latent infection because P27 is not produced during latency. However,
latency may be an extension of the post-viremia recovery process and not a
stage of the initial infection process itself.

Other than transmission from a bite wound, effective transmission requires
prolonged intimate contact. If I were you, I'd retest the cat with another
ELISA. False ELISA-negatives are rare. In the unlikey event the ELISA is
positve, retest with the IFA.

FeLV ELISA positives are not all that reliable because a positive result
indicates cirulating antigen but *not* necessairly a productive,
marrow-origin infection.

Good luck.

Phil.



  #6  
Old December 12th 03, 12:53 AM
Cat Protector
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Posts: n/a
Default

Are your other cats FELV?

--
Panther TEK: Staying On Top Of All Your Computer Needs!
www.members.cox.net/catprotector/panthertek

Cat Galaxy: All Cats, All The Time!
www.catgalaxymedia.com
"Ben Katz" wrote in message
...
I recently rescued a kitten estimated at 6 months old. She has been

spayed,
vaccinated, and tested negative for FIV/FeLV (snap test). My concern is

that
if she has been recently exposed, it could be too early for an accurate
test. She has been isolated from my other kitties in a spare bedroom for

16
days since she was tested. Is 16 days too early for a re-test? What is

the
incubation period for FeLV?

Thanks,

Ben




  #7  
Old December 12th 03, 12:53 AM
Cat Protector
external usenet poster
 
Posts: n/a
Default

Are your other cats FELV?

--
Panther TEK: Staying On Top Of All Your Computer Needs!
www.members.cox.net/catprotector/panthertek

Cat Galaxy: All Cats, All The Time!
www.catgalaxymedia.com
"Ben Katz" wrote in message
...
I recently rescued a kitten estimated at 6 months old. She has been

spayed,
vaccinated, and tested negative for FIV/FeLV (snap test). My concern is

that
if she has been recently exposed, it could be too early for an accurate
test. She has been isolated from my other kitties in a spare bedroom for

16
days since she was tested. Is 16 days too early for a re-test? What is

the
incubation period for FeLV?

Thanks,

Ben




 




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