Vaccincation Question....please help!

"Yngver" wrote in message
...
So has there been any definitive findings on whether or not the FeLV
vaccine
actually works or not, do you know?

There are several FeLV vaccines available. Here's the quote I saw on the
"Stop
Feline Leukemia" Web site:

"Unfortunately the USDA does not have standard requirements for FeLV
vaccines,
so different manufacturers can publish 'Effectiveness Ratings' which
cannot be
compared with each other due to a lack of uniformity in testing terms and
requirements."

I did see a study (can't find it now, of course) which experimentally
exposed a
number of cats and kittens to FeLV, with a group of cats vaccinated and
the
other not vaccinated. I don't know which particular vaccine was used. I
wish I
could recall the details, but I do remember that only one of the
vaccinated
cats developed FeLV, as opposed to about a third of the non-vaccinated
cats. So
what you can say is that FeLV vaccinations will prevent many exposed cats
from
developing FeLV, but not all.


AIDS Res Hum Retroviruses 1996 Mar 20;12(5):379-83

Efficacy of an inactivated feline leukemia virus vaccine.

Hoover EA, Mullins JI, Chu HJ, Wasmoen TL.

Department of Pathology, Colorado State University, Fort Collins 80523, USA.

An inactivated whole-virus FeLV vaccine, developed from a molecularly cloned
FeLV isolate (FeLV-61E-A), was assessed for its ability to protect cats
against
homologous and heterologous virulent viral challenge. The fractions of cats
that
resisted the induction of persistent viremia after FeLV challenge were as
follows: FeLV-61E-A vaccine, 95%; adjuvant controls, 26%; and established
commercial control FeLV vaccine, 35%. The prechallenge mean neutralizing
antibody titers for each group were as follows: FeLV-61E-A vaccine, 1:43;
adjuvant controls, 1:8; and commercial control FeLV vaccine, 1:12. The
prototype FeLV-61E-A vaccine was developed commercially for immunization of
pet
cats by substitution of a proprietary adjuvant and development of stable,
high
antigen production cell lines. This vaccine (Fel-O-Vax) has been studied
extensively, alone and in multivalent combination with other feline virus
vaccines, in seven efficacy trials involving a total of 150 immunized cats.
These studies yielded an FeLV-resistant fraction of 87% in vaccinated cats
as
compared with 8% in adjuvant controls. The duration of immunity induced by
an
FeLV-61E-A commercial vaccine (Fel-O-Vax-LvK IV) was also assessed. One year
after vaccination, 100% of challenged vaccinated cats and none of challenged
controls resisted induction of persistent viremia. The results of these
studies
demonstrate that an inactivated FeLV vaccine prepared from a molecularly
cloned
subgroup A FeLV produces a high level of protective immunity against
heterologous and homologous FeLV infection. This vaccine-induced immunity is
durable for at least 1 year without intervening booster immunization or
exposure
to virus."


Many FeLV vaccine efficacy trials have been conducted over the years --
Efficacy among the various vaccines range between 75% and 90% with most
researchers agreeing on the average vqccine efficacy of about 75-80%.

I don't have time to dig through studies and construct side-by-side
comparisons. But it shouldn't take a comparison for a rational and
reasonable person to realize that the 75% odds of vaccine protection jusify
the .0001% odds of developing a VAS for cats *at risk* of contracting FeLV.

"-L." wrote in message
m...
(Liz) wrote in message
. com...


Vaccinate your cats or don't. The fact is cats DO NOT become immune
to FeLV.

-L.


Remember, Liz is the same lunatic that said calcium oxalate uroliths can be
dissolved with *water* in cats.... and who "corrects" peer-reviewed and
other
studies and surveys to what she thinks they should say and what the
author(s) "really meant"...

Liz is also the psychopath that said cats shouldn't be vaccinated -- even
though she knows for generations, millions of cats would die, she feels its
worth it because not vaccinating cats would produce stronger cats that don't
need vaccinations... How's that?

"-L." wrote in message
m...
(Liz) wrote in message
. com...


Vaccinate your cats or don't. The fact is cats DO NOT become immune
to FeLV.

-L.


Remember, Liz is the same lunatic that said calcium oxalate uroliths can be
dissolved with *water* in cats.... and who "corrects" peer-reviewed and
other
studies and surveys to what she thinks they should say and what the
author(s) "really meant"...

Liz is also the psychopath that said cats shouldn't be vaccinated -- even
though she knows for generations, millions of cats would die, she feels its
worth it because not vaccinating cats would produce stronger cats that don't
need vaccinations... How's that?

Phil P" wrote:

So
what you can say is that FeLV vaccinations will prevent many exposed cats
from
developing FeLV, but not all.


AIDS Res Hum Retroviruses 1996 Mar 20;12(5):379-83

Efficacy of an inactivated feline leukemia virus vaccine.

Hoover EA, Mullins JI, Chu HJ, Wasmoen TL.

Department of Pathology, Colorado State University, Fort Collins 80523, USA.

An inactivated whole-virus FeLV vaccine, developed from a molecularly cloned
FeLV isolate (FeLV-61E-A), was assessed for its ability to protect cats
against
homologous and heterologous virulent viral challenge. The fractions of cats
that
resisted the induction of persistent viremia after FeLV challenge were as
follows: FeLV-61E-A vaccine, 95%; adjuvant controls, 26%; and established
commercial control FeLV vaccine, 35%. The prechallenge mean neutralizing
antibody titers for each group were as follows: FeLV-61E-A vaccine, 1:43;
adjuvant controls, 1:8; and commercial control FeLV vaccine, 1:12. The
prototype FeLV-61E-A vaccine was developed commercially for immunization of
pet
cats by substitution of a proprietary adjuvant and development of stable,
high
antigen production cell lines. This vaccine (Fel-O-Vax) has been studied
extensively, alone and in multivalent combination with other feline virus
vaccines, in seven efficacy trials involving a total of 150 immunized cats.
These studies yielded an FeLV-resistant fraction of 87% in vaccinated cats
as
compared with 8% in adjuvant controls. The duration of immunity induced by
an
FeLV-61E-A commercial vaccine (Fel-O-Vax-LvK IV) was also assessed. One year
after vaccination, 100% of challenged vaccinated cats and none of challenged
controls resisted induction of persistent viremia. The results of these
studies
demonstrate that an inactivated FeLV vaccine prepared from a molecularly
cloned
subgroup A FeLV produces a high level of protective immunity against
heterologous and homologous FeLV infection. This vaccine-induced immunity is
durable for at least 1 year without intervening booster immunization or
exposure
to virus."


Many FeLV vaccine efficacy trials have been conducted over the years --
Efficacy among the various vaccines range between 75% and 90% with most
researchers agreeing on the average vqccine efficacy of about 75-80%.

I don't have time to dig through studies and construct side-by-side
comparisons. But it shouldn't take a comparison for a rational and
reasonable person to realize that the 75% odds of vaccine protection jusify
the .0001% odds of developing a VAS for cats *at risk* of contracting FeLV.

Thank you for finding this and posting it, Phil. If, as a Winn Foundation
article reports, as many as eleven percent of strays are infected with FeLV,
and in urban areas up to 40 percent of roaming cats, it certainly seems
rational to vaccinate any cat that might come into contact with strays or
indoor/outdoor cats.

Phil P" wrote:

So
what you can say is that FeLV vaccinations will prevent many exposed cats
from
developing FeLV, but not all.


AIDS Res Hum Retroviruses 1996 Mar 20;12(5):379-83

Efficacy of an inactivated feline leukemia virus vaccine.

Hoover EA, Mullins JI, Chu HJ, Wasmoen TL.

Department of Pathology, Colorado State University, Fort Collins 80523, USA.

An inactivated whole-virus FeLV vaccine, developed from a molecularly cloned
FeLV isolate (FeLV-61E-A), was assessed for its ability to protect cats
against
homologous and heterologous virulent viral challenge. The fractions of cats
that
resisted the induction of persistent viremia after FeLV challenge were as
follows: FeLV-61E-A vaccine, 95%; adjuvant controls, 26%; and established
commercial control FeLV vaccine, 35%. The prechallenge mean neutralizing
antibody titers for each group were as follows: FeLV-61E-A vaccine, 1:43;
adjuvant controls, 1:8; and commercial control FeLV vaccine, 1:12. The
prototype FeLV-61E-A vaccine was developed commercially for immunization of
pet
cats by substitution of a proprietary adjuvant and development of stable,
high
antigen production cell lines. This vaccine (Fel-O-Vax) has been studied
extensively, alone and in multivalent combination with other feline virus
vaccines, in seven efficacy trials involving a total of 150 immunized cats.
These studies yielded an FeLV-resistant fraction of 87% in vaccinated cats
as
compared with 8% in adjuvant controls. The duration of immunity induced by
an
FeLV-61E-A commercial vaccine (Fel-O-Vax-LvK IV) was also assessed. One year
after vaccination, 100% of challenged vaccinated cats and none of challenged
controls resisted induction of persistent viremia. The results of these
studies
demonstrate that an inactivated FeLV vaccine prepared from a molecularly
cloned
subgroup A FeLV produces a high level of protective immunity against
heterologous and homologous FeLV infection. This vaccine-induced immunity is
durable for at least 1 year without intervening booster immunization or
exposure
to virus."


Many FeLV vaccine efficacy trials have been conducted over the years --
Efficacy among the various vaccines range between 75% and 90% with most
researchers agreeing on the average vqccine efficacy of about 75-80%.

I don't have time to dig through studies and construct side-by-side
comparisons. But it shouldn't take a comparison for a rational and
reasonable person to realize that the 75% odds of vaccine protection jusify
the .0001% odds of developing a VAS for cats *at risk* of contracting FeLV.

Thank you for finding this and posting it, Phil. If, as a Winn Foundation
article reports, as many as eleven percent of strays are infected with FeLV,
and in urban areas up to 40 percent of roaming cats, it certainly seems
rational to vaccinate any cat that might come into contact with strays or
indoor/outdoor cats.

You obviously did not understand at all what I wrote but of course I
predicted that. The immediate effects of vaccinating against FeLV may
be apparently good but definitively not worth the risk. If the risk
were worth it, we would have a vaccine for AIDS and for every other
disease caused by retroviruses in humans. BTW, do you have any studies
showing the efficacy of the vaccine in a natural setting, that is,
challenged with strains that are out there and not the ones they
manipulate in labs?

You obviously did not understand at all what I wrote but of course I
predicted that. The immediate effects of vaccinating against FeLV may
be apparently good but definitively not worth the risk. If the risk
were worth it, we would have a vaccine for AIDS and for every other
disease caused by retroviruses in humans. BTW, do you have any studies
showing the efficacy of the vaccine in a natural setting, that is,
challenged with strains that are out there and not the ones they
manipulate in labs?

"Liz" wrote in message
om...



You obviously did not understand at all what I wrote


You're obviously right! I obviously don't understand your obviously utterly
stupid and obviously nonsensical theories and obviously asinine
conclusions... Obviously the mainstream veterinary community doesn't
understand you either.... You're obviously the only person who understands
you....



but of course I
predicted that.


Of course you did! Clairvoyance is part of your delusion.. That's how you
get all this secret information that's known only to you but unknown to the
mainstream veterinary medical community.... like your utterly stupid
delusion of dissolving calcium oxalate uroliths in cats with water!


The immediate effects of vaccinating against FeLV may
be apparently good


Yeah, Einstein, I'd say protecting cats at risk of contracting a fatal
disease may be "apparently good"...


but definitively not worth the risk.


Lets see.... the vaccine has at least a 75% efficacy with a 0.0001% risk
factor... and you say its "definitively not worth the risk.."? ...and you
still don't think there's something very seriously wrong with you?


If the risk
were worth it, we would have a vaccine for AIDS and for every other
disease caused by retroviruses in humans.


Human AIDS and FeLV aren't caused by the same virus, you backwoods babbling
idiot ,.... The human and Feline immunodeficiency viruses are classified as
Lentivirinae or type E Retroviridae and are distinct from the FeLV. The
FeLV belongs to the subfamily Oncovirinae of the Retroviridae family.

BTW, do you have any studies

Why do you ask? Did you run out of studies to manipulate, and deliberately
misinterpret?

"Liz" wrote in message
om...



You obviously did not understand at all what I wrote


You're obviously right! I obviously don't understand your obviously utterly
stupid and obviously nonsensical theories and obviously asinine
conclusions... Obviously the mainstream veterinary community doesn't
understand you either.... You're obviously the only person who understands
you....



but of course I
predicted that.


Of course you did! Clairvoyance is part of your delusion.. That's how you
get all this secret information that's known only to you but unknown to the
mainstream veterinary medical community.... like your utterly stupid
delusion of dissolving calcium oxalate uroliths in cats with water!


The immediate effects of vaccinating against FeLV may
be apparently good


Yeah, Einstein, I'd say protecting cats at risk of contracting a fatal
disease may be "apparently good"...


but definitively not worth the risk.


Lets see.... the vaccine has at least a 75% efficacy with a 0.0001% risk
factor... and you say its "definitively not worth the risk.."? ...and you
still don't think there's something very seriously wrong with you?


If the risk
were worth it, we would have a vaccine for AIDS and for every other
disease caused by retroviruses in humans.


Human AIDS and FeLV aren't caused by the same virus, you backwoods babbling
idiot ,.... The human and Feline immunodeficiency viruses are classified as
Lentivirinae or type E Retroviridae and are distinct from the FeLV. The
FeLV belongs to the subfamily Oncovirinae of the Retroviridae family.

BTW, do you have any studies

Why do you ask? Did you run out of studies to manipulate, and deliberately
misinterpret?