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#22
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As stated earlier the urine culture results came back negative. My vet is assuming that she has a kidney infection but doesn't know what kind of organism it is (if it's really an infection). So it may not be easy to say if enrofloxacin or Orbifloxacin will work better in this case. Thanks again for the info. I should add that in my case, my cat was clearly very sick and it wouldn't have been prudent to waffle about whether to switch her from Baytril to Orbax when she had not responded to other antibiotics prior to administering Baytil. In your case, it's not even clear that your cat has an infection, correct? The evidence was the blood in the urine sample, but is there any other sign of infection? My cat was running a very high fever. Here are some references you can look at: http://www.vetmedcenter.com/professi...688&doctype=ED http://www.tufts.edu/vet/vet_common/..._march2003.pdf This second one from Tufts may have the info you are looking for. It describes studies designed to determine a correlation between dosage of Baytril and Orbax and retinal degeneration in cats. While both drugs produced incidences of blindness at high dosages, the mfr of Orbax determined the drug to be safe at a dosage of 15 mg/kg per day (although one cat did develop retinal degeneration on this dosage), while Bayer's toxicity test of Baytril found no incidence of retinal damage at the currently recommended max dosage of 5 mg/kg per day. You may want to show this article to your vet, if you still want to argue the case with him. |
#23
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ospam (Yngver) wrote: wrote: As stated earlier the urine culture results came back negative. My vet is assuming that she has a kidney infection but doesn't know what kind of organism it is (if it's really an infection). So it may not be easy to say if enrofloxacin or Orbifloxacin will work better in this case. Thanks again for the info. I should add that in my case, my cat was clearly very sick and it wouldn't have been prudent to waffle about whether to switch her from Baytril to Orbax when she had not responded to other antibiotics prior to administering Baytil. In your case, it's not even clear that your cat has an infection, correct? The evidence was the blood in the urine sample, but is there any other sign of infection ? My cat was running a very high fever. Here are some references you can look at: http://www.vetmedcenter.com/professi...688&doctype=ED http://www.tufts.edu/vet/vet_common/..._march2003.pdf This second one from Tufts may have the info you are looking for. It describes studies designed to determine a correlation between dosage of Baytril and Orbax and retinal degeneration in cats. While both drugs produced incidences of blindness at high dosages, the mfr of Orbax determined the drug to be safe at a dosage of 15 mg/kg per day (although one cat did develop retinal degeneration on this dosage), while Bayer's toxicity test of Baytril found no incidence of retinal damage at the currently recommended max dosage of 5 mg/kg per day. You may want to show this article to your vet, if you still want to argue the case with him. Thanks Yngver. My cat lost some weight a couple of weeks ago (which I thought was due to all the smoke from the wild fires) but has gained most of it back. Right now beside the high red blood cell counts in the urine she's doing just fine. I don't even have to give her Prednisone (for the IBD) that often any more. Another option is to check her urine again in a week or two. I think there's a good chance it will be normal again. |
#24
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ospam (Yngver) wrote: wrote: As stated earlier the urine culture results came back negative. My vet is assuming that she has a kidney infection but doesn't know what kind of organism it is (if it's really an infection). So it may not be easy to say if enrofloxacin or Orbifloxacin will work better in this case. Thanks again for the info. I should add that in my case, my cat was clearly very sick and it wouldn't have been prudent to waffle about whether to switch her from Baytril to Orbax when she had not responded to other antibiotics prior to administering Baytil. In your case, it's not even clear that your cat has an infection, correct? The evidence was the blood in the urine sample, but is there any other sign of infection ? My cat was running a very high fever. Here are some references you can look at: http://www.vetmedcenter.com/professi...688&doctype=ED http://www.tufts.edu/vet/vet_common/..._march2003.pdf This second one from Tufts may have the info you are looking for. It describes studies designed to determine a correlation between dosage of Baytril and Orbax and retinal degeneration in cats. While both drugs produced incidences of blindness at high dosages, the mfr of Orbax determined the drug to be safe at a dosage of 15 mg/kg per day (although one cat did develop retinal degeneration on this dosage), while Bayer's toxicity test of Baytril found no incidence of retinal damage at the currently recommended max dosage of 5 mg/kg per day. You may want to show this article to your vet, if you still want to argue the case with him. Thanks Yngver. My cat lost some weight a couple of weeks ago (which I thought was due to all the smoke from the wild fires) but has gained most of it back. Right now beside the high red blood cell counts in the urine she's doing just fine. I don't even have to give her Prednisone (for the IBD) that often any more. Another option is to check her urine again in a week or two. I think there's a good chance it will be normal again. |
#25
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ospam (Yngver) wrote: wrote: As stated earlier the urine culture results came back negative. My vet is assuming that she has a kidney infection but doesn't know what kind of organism it is (if it's really an infection). So it may not be easy to say if enrofloxacin or Orbifloxacin will work better in this case. Thanks again for the info. I should add that in my case, my cat was clearly very sick and it wouldn't have been prudent to waffle about whether to switch her from Baytril to Orbax when she had not responded to other antibiotics prior to administering Baytil. In your case, it's not even clear that your cat has an infection, correct? The evidence was the blood in the urine sample, but is there any other sign of infection ? My cat was running a very high fever. Here are some references you can look at: http://www.vetmedcenter.com/professi...688&doctype=ED http://www.tufts.edu/vet/vet_common/..._march2003.pdf This second one from Tufts may have the info you are looking for. It describes studies designed to determine a correlation between dosage of Baytril and Orbax and retinal degeneration in cats. While both drugs produced incidences of blindness at high dosages, the mfr of Orbax determined the drug to be safe at a dosage of 15 mg/kg per day (although one cat did develop retinal degeneration on this dosage), while Bayer's toxicity test of Baytril found no incidence of retinal damage at the currently recommended max dosage of 5 mg/kg per day. You may want to show this article to your vet, if you still want to argue the case with him. Thanks Yngver. My cat lost some weight a couple of weeks ago (which I thought was due to all the smoke from the wild fires) but has gained most of it back. Right now beside the high red blood cell counts in the urine she's doing just fine. I don't even have to give her Prednisone (for the IBD) that often any more. Another option is to check her urine again in a week or two. I think there's a good chance it will be normal again. |
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#28
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#29
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wrote in message nk.net... My cat Casper had her teeth cleaned a few weeks ago and the vet told me that she had a high level of red blood cell in her urine. After 1 week of Clavamox the level was still high and the urine culture results came back negative, i.e. they weren't able to grow anything. So my vet is saying that she probably has an infection in the kidneys and wants her to take Enrofloxacin. Today I faxed him the following article : http://www.vin.com/VINDBPub/SearchPB...00/PR00528.htm "Enrofloxacin has recently been associated with retinal degeneration in cats at the recommended dose rate. Affected cats present with rapid onset of blindness after systemic enrofloxacin administration. Affected cats have typical lesions of retinal degeneration. Discontinuation of enrofloxacin as soon as visual problems are noted may result in improvement in vision in some, but not all cases. No doubt guidelines will be forthcoming regarding the use of enrofloxacin in cats in view of increasing numbers of anecdotal adverse reaction reports as well as published data or its potential toxicity." I asked him if Orbifloxacin (recommended by Phil) is safer but he said that there are not enough statistics to show that it is safer. He said there are a lot more statistics on Enrofloxacin because it's been used on millions of cats during the past 10 years. So I told him that I wanted to think about it for a few days. What would you do in this situation ? Casper seems to be doing better and has gained back some weight during the past week. She's recovering from IBD and doesn't need Prednisone that much any more but this probably has nothing to do with blood in the urine. Thanks in advance for your suggestions. Chester, I would go with Orbax -- so do all four of our vets - who see considerably more animals per year than the average vet. There's really no rational reason for using Baytril. Orbax is same-class antibiotic, its safer, more potent, and requires a smaller dose... Its even less expensive... which might free-up money for additional tests and treatment, if needed, for people on a tight budget. Remember, the extensive original efficacy testing found Baytril to be most efficacious at 20 mg/kg... Now, after almost *5 years* of numerous reports of blindness in cats, Bayer reduced the dosage by *75%* (5 mg/kg)... If Baytril was *really* efficacious at *25%* of the original recommended dose, why wasn't the *original* recommended dose 5 mg/kg??? Its the same principal as taking 1/2 an aspirin instead of two and expecting the same results... So, if I were you, I would take the arguments by the Baytril proponents with a grain a salt... Some people are awakened with a feather... Others need to be hit with a sledgehammer before they wake up... Have you tried Hill's Prescription Diet d/d for Casper's IBD? It contains a single protein source. We've had *excellent* results with d/d in our IBD cats. Good luck. Phil. |
#30
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wrote in message nk.net... My cat Casper had her teeth cleaned a few weeks ago and the vet told me that she had a high level of red blood cell in her urine. After 1 week of Clavamox the level was still high and the urine culture results came back negative, i.e. they weren't able to grow anything. So my vet is saying that she probably has an infection in the kidneys and wants her to take Enrofloxacin. Today I faxed him the following article : http://www.vin.com/VINDBPub/SearchPB...00/PR00528.htm "Enrofloxacin has recently been associated with retinal degeneration in cats at the recommended dose rate. Affected cats present with rapid onset of blindness after systemic enrofloxacin administration. Affected cats have typical lesions of retinal degeneration. Discontinuation of enrofloxacin as soon as visual problems are noted may result in improvement in vision in some, but not all cases. No doubt guidelines will be forthcoming regarding the use of enrofloxacin in cats in view of increasing numbers of anecdotal adverse reaction reports as well as published data or its potential toxicity." I asked him if Orbifloxacin (recommended by Phil) is safer but he said that there are not enough statistics to show that it is safer. He said there are a lot more statistics on Enrofloxacin because it's been used on millions of cats during the past 10 years. So I told him that I wanted to think about it for a few days. What would you do in this situation ? Casper seems to be doing better and has gained back some weight during the past week. She's recovering from IBD and doesn't need Prednisone that much any more but this probably has nothing to do with blood in the urine. Thanks in advance for your suggestions. Chester, I would go with Orbax -- so do all four of our vets - who see considerably more animals per year than the average vet. There's really no rational reason for using Baytril. Orbax is same-class antibiotic, its safer, more potent, and requires a smaller dose... Its even less expensive... which might free-up money for additional tests and treatment, if needed, for people on a tight budget. Remember, the extensive original efficacy testing found Baytril to be most efficacious at 20 mg/kg... Now, after almost *5 years* of numerous reports of blindness in cats, Bayer reduced the dosage by *75%* (5 mg/kg)... If Baytril was *really* efficacious at *25%* of the original recommended dose, why wasn't the *original* recommended dose 5 mg/kg??? Its the same principal as taking 1/2 an aspirin instead of two and expecting the same results... So, if I were you, I would take the arguments by the Baytril proponents with a grain a salt... Some people are awakened with a feather... Others need to be hit with a sledgehammer before they wake up... Have you tried Hill's Prescription Diet d/d for Casper's IBD? It contains a single protein source. We've had *excellent* results with d/d in our IBD cats. Good luck. Phil. |
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