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Testing for FeLV and FIV - question
How long should I wait to test a cat after it's possibly been exposed
to FeLV and FIV? I would hate to get a false negative because I had the test done too soon. |
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Testing for FeLV and FIV - question
"Mikey" wrote in message oups.com... How long should I wait to test a cat after it's possibly been exposed to FeLV and FIV? I would hate to get a false negative because I had the test done too soon. Depends on which test you use. The in-house ELISA (enzyme-linked immunosorbent assay) Snap test can detect *circulating* FeLV antigen in about 2-4 weeks or less. However, a positive ELISA Snap result cannot differentiate a transient infection from a persistent infection or predict if the cat will become persistently infected. IOW, a positive ELISA Snap *does not* mean your cat is infected for life. Most healthy cats over 4 months clear the virus in 4-8 weeks after exposure. All ELISA positives should be confirmed by the IFA. About 40-50% of ELISA-positive cats *are not* persistently infected. So, don't kill or get rid of your cat because of an ELISA positive result. The IFA (immunofluorescent antibody) assay detects FeLV antigen in the leukocytes and platelets. A positive result indicates a productive infection in the bone marrow cells- which usually means the cat will be infected for life. It usually takes about 4 weeks for bone marrow cells to become infected- but could take as long as 12. Most IFA-positive cats are persistently infected for life-- but could still have a good quality of life for several years. I had an FeLV cat that lived a good quality of life for 6 years after diagnosis. Effective transmission requires prolonged, intimate contact or a bite wound from an infected cat. Passing contact usually ain't gonna do it. Its also possible for a cat to test ELISA positive and IFA negative. This could mean the cat is transiently infected and is in process of clearing the virus- or the cat is in the process of developing a persistent infection, or the cat is harboring the virus in some *non-myeloid* compartment in the body. For FIV- it usually takes about 8 -12 weeks for antibodies to develop after the initial infection. Kittens 6-8 months old can test positive for FIV from receiving FIV antibodies from their mother through colostrum *without* being infected. An FIV-vaccinated cat will also test positive as well as her kittens. There's only one DNA test that can differentiate FIV-vaccinated cats from FIV-infected cats and its only available at UC-Davis. Effective transmission usually requires a bite wound. Normal contact ain't gonna do it. With good care, FIV cats can live near normal lifespans. Best of luck, Phil |
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